Molecular detection and characterisation of circulating tumour cells and micrometastases in solid tumours.

@article{Ghossein2000MolecularDA,
  title={Molecular detection and characterisation of circulating tumour cells and micrometastases in solid tumours.},
  author={Ronald A. Ghossein and Sanchita Bhattacharya},
  journal={European journal of cancer},
  year={2000},
  volume={36 13 Spec No},
  pages={
          1681-94
        }
}
The detection and molecular characterisation of circulating tumour cells (CTC) and micrometastases may have important prognostic and therapeutic implications. Because their numbers are very small, these tumour cells are not easily detected using conventional methods. In the last decade, numerous groups have attempted to detect occult tumour cells in solid malignancies using the highly sensitive reverse transcriptase polymerase chain reaction (RT-PCR). These assays were in the vast majority… CONTINUE READING

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