Molecular design of protein-based nanocapsules for stimulus-responsive characteristics.


Hsp16.5, a small heat-shock protein (sHSP) from hyperthermophilic archaeon, forms a homogeneous complex comprised of 24 subunits with a molecular mass of 400 kDa. This complex self-organizes under physiological conditions, and the structure of the complex is a nanoscale spherical capsule with small pores. Furthermore, this natural nanocapsule exhibits very… (More)
DOI: 10.1016/j.bmc.2008.11.013


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