Molecular design of allergy vaccines.

  title={Molecular design of allergy vaccines.},
  author={Birgit Linhart and Rudolf Valenta},
  journal={Current opinion in immunology},
  volume={17 6},
Recombinant-allergen-based diagnostic tests enable the dissection and monitoring of the molecular reactivity profiles of allergic patients, resulting in more specific diagnosis, disease monitoring, prevention and therapy. In vitro experiments, animal studies and clinical trials in patients demonstrate that allergenic molecules can be engineered to induce different immune responses ranging from tolerance to vigorous immunity. The available data thus suggest that molecular engineering of the… CONTINUE READING