Molecular design of Mycoplasma hominis Vaa adhesin.

  title={Molecular design of Mycoplasma hominis Vaa adhesin.},
  author={Thomas Boesen and Natalya U. Fedosova and Morten Kjeldgaard and Svend Birkelund and Gunna Christiansen},
  journal={Protein science : a publication of the Protein Society},
  volume={10 12},
The variable adherence-associated (Vaa) adhesin of the opportunistic human pathogen Mycoplasma hominis is a surface-exposed, membrane-associated protein involved in the attachment of the bacterium to host cells. The molecular masses of recombinant 1 and 2 cassette forms of the protein determined by a light-scattering (LS) method were 23.9 kD and 36.5 kD, respectively, and corresponded to their monomeric forms. Circular dichroism (CD) spectroscopy of the full-length forms indicated that the Vaa… CONTINUE READING