Molecular cytogenetic evidence of t(14;18)(IGH;BCL2) in a substantial proportion of primary cutaneous follicle center lymphomas.

@article{Streubel2006MolecularCE,
  title={Molecular cytogenetic evidence of t(14;18)(IGH;BCL2) in a substantial proportion of primary cutaneous follicle center lymphomas.},
  author={Berthold Streubel and Brigitte Scheucher and Julia B Valencak and Daniela Huber and Peter Petzelbauer and Franz Trautinger and Felix Weihsengruber and Christine Mannhalter and Lorenzo Cerroni and Andreas Chott},
  journal={The American journal of surgical pathology},
  year={2006},
  volume={30 4},
  pages={529-36}
}
In contrast to nodal follicular lymphoma, limited data exist on genetic changes in primary cutaneous follicular lymphoma (primary cutaneous follicle center lymphoma according to WHO-EORTC). The detection rate of the BCL2 rearrangement, representing the characteristic t(14;18)(q32;q21) underlying follicular lymphoma, by polymerase chain reaction (PCR) has been reported to vary over a wide range (0%-41%), and only a few cases have been studied by molecular cytogenetic techniques such as… CONTINUE READING
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