Molecular cytogenetic characterization and clinical relevance of additional, complex and/or variant chromosome abnormalities in acute promyelocytic leukemia

@article{Xu2001MolecularCC,
  title={Molecular cytogenetic characterization and clinical relevance of additional, complex and/or variant chromosome abnormalities in acute promyelocytic leukemia},
  author={Lan Xu and W Zhao and S-M Xiong and X Su and Meng Zhao and C Wang and Y Gao and C Niu and Qi Cao and B Gu and Y. Zhu and Jun Gu and Jiong Hu and H. -C. Yan and Z Shen and Z Chen and S Chen},
  journal={Leukemia},
  year={2001},
  volume={15},
  pages={1359-1368}
}
Acute promyelocytic leukemia (APL) is characterized by typical morphological manifestation, t(15;17) translocation and active response to all-trans retinoic acid (ATRA) in the great majority of patients. However, a subset of APL cases may present atypical phenotypic, cytogenetic or molecular features at different stages of the disease. The biological and clinical significance of these features sometimes remains obscure. In this study, 284 APL patients were cytogenetically analyzed and precise… CONTINUE READING
28 Citations
53 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Similar Papers

Loading similar papers…