Molecular control of iron transport.

@article{Ganz2007MolecularCO,
  title={Molecular control of iron transport.},
  author={Tomas Ganz},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2007},
  volume={18 2},
  pages={394-400}
}
  • Tomas Ganz
  • Published 2007 in
    Journal of the American Society of Nephrology…
The iron-regulatory hormone hepcidin is a 25-amino acid peptide that is synthesized in hepatocytes. Hepcidin binds to the cellular iron export channel ferroportin and causes its internalization and degradation and thereby decreases iron efflux from iron exporting tissues into plasma. By this mechanism, hepcidin inhibits dietary iron absorption, the efflux of recycled iron from splenic and hepatic macrophages, and the release of iron from storage in hepatocytes. Hepcidin synthesis is stimulated… CONTINUE READING
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The solution structure of human hepcidin , a peptide hormone with 398 Journal of the American Society of

  • HN Hunter, DB Fulton, T Ganz, HJ Vogel
  • Nephrology J Am Soc Nephrol
  • 2007

The solution structure of human hepcidin, a peptide hormone with 398 Journal of the American Society of Nephrology

  • HN Hunter, DB Fulton, T Ganz, HJ Vogel
  • J Am Soc Nephrol
  • 2007

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