Molecular control of circadian metabolic rhythms.

  title={Molecular control of circadian metabolic rhythms.},
  author={SiMing Li and Jiandie D Lin},
  journal={Journal of applied physiology},
  volume={107 6},
Circadian metabolic rhythms are fundamental to the control of nutrient and energy homeostasis, as well as the pathogenesis of metabolic disease, such as obesity, lipid disorders, and type 2 diabetes. This temporal organization of tissue metabolism is coordinated through reciprocal cross talk between the biological timing system and the metabolic regulatory networks. In this review, we discuss the signaling mechanisms that serve to couple metabolic regulation to the circadian pacemaker, in… CONTINUE READING

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