Molecular conformation and filtration properties of anionic Ficoll.

@article{Groszek2010MolecularCA,
  title={Molecular conformation and filtration properties of anionic Ficoll.},
  author={Joseph J Groszek and Lingyan Li and Nicholas Carmen Ferrell and Ross A Smith and C. A. Zorman and Christina L Hofmann and Shuvo Roy and William H Fissell},
  journal={American journal of physiology. Renal physiology},
  year={2010},
  volume={299 4},
  pages={F752-7}
}
The physiology of glomerular permselectivity remains mechanistically obscure, despite its importance in human disease. Although electrical contributions to glomerular permselectivity have long been considered important, two recent reports demonstrated enhanced glomerular permeability to anionic versus neutral polysaccharides. The interpretation of these observations is complicated by confounding of the effects of chemical modification on charge with effects on size and shape. In this report… CONTINUE READING

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