Molecular composition of GABAC receptors

  title={Molecular composition of GABAC receptors},
  author={R. Enz and G. Cutting},
  journal={Vision Research},
  • R. Enz, G. Cutting
  • Published 1998
  • Chemistry, Medicine
  • Vision Research
  • In the central nervous system inhibitory neurotransmission is primarily achieved through activation of receptors for gamma-aminobutyric acid (GABA). Three types of GABA receptors have been identified on the basis of their pharmacology and electrophysiology. The predominant type, termed GABAA and a recently identified type, GABAC, have integral chloride channels, whereas GABAB receptors couple to separate K+ or Ca2+ channels via G-proteins. By analogy to nicotinic acetylcholine receptors, native… CONTINUE READING
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