Molecular communication between tumor-associated fibroblasts and head and neck squamous cell carcinoma.

@article{Leef2013MolecularCB,
  title={Molecular communication between tumor-associated fibroblasts and head and neck squamous cell carcinoma.},
  author={George Leef and Sufi Mary Thomas},
  journal={Oral oncology},
  year={2013},
  volume={49 5},
  pages={
          381-6
        }
}
Over the past few decades, it has become increasingly clear that the lethality of cancers depends on more than the malignant cells themselves. The environment those malignant cells are exposed to is just as important a determinant of their behavior. Head and neck squamous cell carcinoma (HNSCC) is both common and deadly. It is the 6th most frequently occurring cancers, and prognosis is still generally poor. Recent evidence indicates that activated fibroblasts residing within the tumor stroma… CONTINUE READING

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