Molecular cloning of the cDNA coding for properdin, a positive regulator of the alternative pathway of human complement.

@article{Nolan1991MolecularCO,
  title={Molecular cloning of the cDNA coding for properdin, a positive regulator of the alternative pathway of human complement.},
  author={Kathleen F. Nolan and Wilhelm Schwaeble and Stefan Kaluz and Manfred Paul Dierich and Kenneth B. M. Reid},
  journal={European journal of immunology},
  year={1991},
  volume={21 3},
  pages={771-6}
}
Northern blot analysis indicated that the mRNA for human properdin is approximately 1.5 kb long and that its level in U-937 cells is increased by pretreating the cells with phorbol 12-myristate 13-acetate (PMA). Using a human genomic probe clones coding for human properdin were isolated from a lambda gt10 cDNA library derived from PMA-treated U-937 cells… CONTINUE READING