Molecular cloning of the bile salt-dependent lipase of ferret lactating mammary gland: an overview of functional residues.

@article{Sbarra1998MolecularCO,
  title={Molecular cloning of the bile salt-dependent lipase of ferret lactating mammary gland: an overview of functional residues.},
  author={V{\'e}ronique Sbarra and Nadine Bruneau and Eric M. Mas and Margit Hamosh and Dominique Lombardo and Paul Hamosh},
  journal={Biochimica et biophysica acta},
  year={1998},
  volume={1393 1},
  pages={80-9}
}
Ferret lactating mammary gland bile salt-dependent lipase (BSDL, EC 3.1.1.-) has been cloned by RT-PCR. The open reading frame consists of 1869 nucleotides which encode 623 amino acids of the functional enzyme. When compared to other species, the greatest homology is observed between residues 1 and 484, with little or no homology at the C-terminal end where seven repeated segments of similar sequence are located. Ferret mammary gland BSDL retains residues involved in the active site and the… CONTINUE READING

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