Molecular cloning of the amino-terminal region of a rat MUC 2 mucin gene homologue. Evidence for expression in both intestine and airway.

@article{Ohmori1994MolecularCO,
  title={Molecular cloning of the amino-terminal region of a rat MUC 2 mucin gene homologue. Evidence for expression in both intestine and airway.},
  author={Haruo Ohmori and Austin F. Dohrman and Marianne Gallup and Takeshi Tsuda and Hisashi Kai and James R. Gum and Young Soo Kim and Carol B. Basbaum},
  journal={The Journal of biological chemistry},
  year={1994},
  volume={269 27},
  pages={17833-40}
}
To obtain cDNAs for analysis of mucin gene transcription in rat models of human disease, we screened a rat intestinal cDNA library in lambda ZAPII using an upstream non-tandem repeat cDNA fragment of the human MUC 2 gene (Gum, J., Hicks, J., Toribara, N., Rothe, E., Lagace, R., and Y., K. (1992) J. Biol. Chem. 267, 21375-21383). Three cDNAs, 1-1, 8-1, and 21-1, were isolated. A translation start site was found in cDNA 21-1. Combined nucleotide sequence for the three cDNAs contained an open… CONTINUE READING

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