Molecular cloning of tenomodulin, a novel chondromodulin-I related gene.

@article{Shukunami2001MolecularCO,
  title={Molecular cloning of tenomodulin, a novel chondromodulin-I related gene.},
  author={Chisa Shukunami and Yasuo Oshima and Yuji Hiraki},
  journal={Biochemical and biophysical research communications},
  year={2001},
  volume={280 5},
  pages={1323-7}
}
Murine expressed sequence tags (EST) showing homology with chondromodulin-I (ChM-I) were identified. Cloning of the full-length cDNA revealed a novel protein (317 amino acid residues) having a domain homologous to ChM-I, and we termed it tenodmoulin (TeM). The predicted amino acid sequence revealed 33% overall identity with mouse ChM-I precursor. Overall structural features were conserved well in TeM, including a single transmembrane domain at the N-terminal region and the putative… CONTINUE READING