Molecular cloning of cDNA coding for rat proliferating cell nuclear antigen (PCNA)/cyclin.

@article{Matsumoto1987MolecularCO,
  title={Molecular cloning of cDNA coding for rat proliferating cell nuclear antigen (PCNA)/cyclin.},
  author={Kyomu Matsumoto and Tetsuya Moriuchi and Takehiko Koji and Paul K. Nakane},
  journal={The EMBO journal},
  year={1987},
  volume={6 3},
  pages={637-42}
}
The 'proliferating cell nuclear antigen' (PCNA), also known as cyclin, appears at the G1/S boundary in the cell cycle. Because of its possible relationship with cell proliferation, PCNA/cyclin has been receiving attention. PCNA/cyclin is a non-histone acidic nuclear protein with an apparent mol. wt of 33000-36000. The amino acid composition and the sequence of the first 25 amino acids of rabbit PCNA/cyclin are known. Using an oligonucleotide probe corresponding to the sequence of the first five… CONTINUE READING

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