Molecular cloning of a second form of rac protein kinase.

  title={Molecular cloning of a second form of rac protein kinase.},
  author={Pamela F Jones and Teresa Jakubowicz and Brian A. Hemmings},
  journal={Cell regulation},
  volume={2 12},
A novel serine/threonine protein kinase (termed rac-PK) has recently been identified and cloned from cDNA libraries derived from the human cell lines MCF-7 and WI38. A second form of this protein kinase, termed rac protein kinase beta, has been identified from cDNAs derived from the same cell lines. These two closely related forms show 90% homology, although the beta form with a predicted Mr 60,200 has a carboxyl terminal extension of 40 amino acids in comparison to the alpha form. This… CONTINUE READING


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