Molecular cloning of a novel mouse gene with predominant muscle and neural expression

  title={Molecular cloning of a novel mouse gene with predominant muscle and neural expression},
  author={John G. Geisler and Lisa J. Stubbs and Wyeth W. Wasserman and Michael L. Mucenski},
  journal={Mammalian Genome},
Because numerous diseases affect the muscle and nervous systems, it is important to identify and characterize genes that may play functional roles in these tissues. Sequence analysis of a 106-kb region of human Chromosome (Chr) 19ql3.2 revealed a novel gene with homology to the Neuroendocrine-specific protein (NSP), and it has, therefore, been designated NSP-like 1 (Nspl1). We isolated the mouse homolog of this gene and performed extensive expression analysis of both the mouse and human genes… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 10 extracted citations


Publications referenced by this paper.
Showing 1-10 of 49 references

Cloning and expression of alternative transcripts of a novel neuroendocrine-specific gene and identification of its 135kDa translational product

  • A Roebroek, H van de Velde, A Van Bokhoven, J Broers, F Ramaekers, Ven W Van de
  • J Biol Chem
  • 1993
Highly Influential
6 Excerpts

Characterization of mouse Nspll gene calcium channel gene are associated with seizures , cerebellar degeneration , and ataxia in tottering and leaner mutant mice

  • L Duret, P Bucher
  • Mamm Genome
  • 1997

Consortium : an integrated molecular analysis of genomes and their expression

  • E. M.A.G.
  • Genomics
  • 1996

Similar Papers

Loading similar papers…