Molecular cloning of a novel mouse gene with predominant muscle and neural expression

@article{Geisler1998MolecularCO,
  title={Molecular cloning of a novel mouse gene with predominant muscle and neural expression},
  author={John G. Geisler and Lisa J. Stubbs and Wyeth W. Wasserman and Michael L. Mucenski},
  journal={Mammalian Genome},
  year={1998},
  volume={9},
  pages={274-282}
}
Because numerous diseases affect the muscle and nervous systems, it is important to identify and characterize genes that may play functional roles in these tissues. Sequence analysis of a 106-kb region of human Chromosome (Chr) 19ql3.2 revealed a novel gene with homology to the Neuroendocrine-specific protein (NSP), and it has, therefore, been designated NSP-like 1 (Nspl1). We isolated the mouse homolog of this gene and performed extensive expression analysis of both the mouse and human genes… CONTINUE READING

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