Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13.

@article{Nagira1997MolecularCO,
  title={Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13.},
  author={Morio Nagira and Toshio Imai and Kunio Hieshima and Jun Kusuda and Maaret Ridanp{\"a}{\"a} and Shingo Takagi and Mikio Nishimura and Mayumi Kakizaki and H. Nomiyama and Osamu Yoshie},
  journal={The Journal of biological chemistry},
  year={1997},
  volume={272 31},
  pages={19518-24}
}
By searching the Expressed Sequence Tag (EST) data base, we identified partial cDNA sequences potentially encoding a novel human CC chemokine. We determined the entire cDNA sequence which encodes a highly basic polypeptide of 134 amino acids total with a putative signal peptide of 23 amino acids. The predicted mature protein of 111 amino acids has the four canonical cysteine residues and shows 21-33% identity to other human CC chemokines, but has a unique carboxyl-terminal extension of about 30… CONTINUE READING