Molecular cloning, functional expression, and pharmacological characterization of 5-hydroxytryptamine3 receptor cDNA and its splice variants from guinea pig.

Abstract

Polymerase chain reaction and rapid amplification of cDNA ends were used to isolate cDNAs encoding a 5-hydroxytryptamine3 (5-HT3) receptor subunit and its splice variants from guinea pig intestine. The amino acid sequence predicted from this cDNA is 81% homologous to the murine 5-HT3 receptor subunits cloned from NCB20 and N1E-115 cells. The splice variants… (More)

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@article{Lankiewicz1998MolecularCF, title={Molecular cloning, functional expression, and pharmacological characterization of 5-hydroxytryptamine3 receptor cDNA and its splice variants from guinea pig.}, author={S Lankiewicz and Nicole Lobitz and Christian Horst Wetzel and Rainer Rupprecht and Guenter Gisselmann and Hanns Hatt}, journal={Molecular pharmacology}, year={1998}, volume={53 2}, pages={202-12} }