Molecular cloning, expression, and characterization of the human mitogen-activated protein kinase p44erk1.

Abstract

p44erk1 is a member of a family of tyrosyl-phosphorylated and mitogen-activated protein (MAP) kinases that participate in cell cycle control. A full-length erk1 cDNA was isolated from a human hepatoma cell line (Hep G2) library. The erk1 cDNA clone shared approximately 96% predicted amino acid identity with partial sequences of rodent erk1 cognates, and the… (More)

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@article{Charest1993MolecularCE, title={Molecular cloning, expression, and characterization of the human mitogen-activated protein kinase p44erk1.}, author={David L. Charest and Guy P. Mordret and Kenneth W. Harder and Frank Robert Jirik and Steven Pelech}, journal={Molecular and cellular biology}, year={1993}, volume={13 8}, pages={4679-90} }