Molecular cloning and sequencing of the murine c-fgr gene.


The c-fgr gene is a member of the tyrosine kinase family of proto-oncogenes and is expressed exclusively in hemopoietic cells. We found that c-fgr was expressed at high levels in a limited subset of murine monocyte/macrophage tumors that were induced by the c-myc oncogene, in cells representing late stages of monocyte differentiation. A cDNA clone was… (More)


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