Molecular cloning and sequencing of the gene encoding human angiotensin II type 1 receptor.

@article{Furuta1992MolecularCA,
  title={Molecular cloning and sequencing of the gene encoding human angiotensin II type 1 receptor.},
  author={Hiroki Furuta and D F Guo and Tadashi Inagami},
  journal={Biochemical and biophysical research communications},
  year={1992},
  volume={183 1},
  pages={8-13}
}
The gene of human angiotensin II type 1 (AT1) receptor was isolated from a lymphocyte genomic library. The coding region of the human AT1 receptor gene was contained in a single exon coding segment of the gene indicating an intronless structure of the coding region. The amino acid sequence of human AT1 receptor deduced from its base sequence has 359 amino acids and showed a high degree of sequence identity to bovine and rat AT1 receptor sequences. Amino acid substitutions specific to the human… CONTINUE READING

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