Molecular cloning and sequencing of a human hepatitis delta (δ) virus RNA

@article{Makino1987MolecularCA,
  title={Molecular cloning and sequencing of a human hepatitis delta (δ) virus RNA},
  author={S. Makino and Ming-Fu Chang and C. Shieh and T. Kamahora and D. M. Vannier and S. Govindarajan and M. C. Lai},
  journal={Nature},
  year={1987},
  volume={329},
  pages={343-346}
}
  • S. Makino, Ming-Fu Chang, +4 authors M. C. Lai
  • Published 1987
  • Biology
  • Nature
  • Human hepatitis delta (δ) virus (HDV) is a form of defective virus, which infects humans only in the presence of a co-infecting hepatitis B virus (HBV), HDV superinfection in a chronic HBV carrier often results in severe chronic hepatitis and cirrhosis, whereas acute HDV and HBV co-infection is frequently associated with fulminant hepatitis1–3. HDV consists of a 36-nm particle; which contains an envelope with HBV surface antigen, and a nucleocapsid containing the hepatitis δ-antigen (HDAg) and… CONTINUE READING
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