Molecular cloning and physical mapping of the DNA of bovine adenovirus serotype 4; study of the DNA homology among bovine, human and porcine adenoviruses.

@article{Benk1990MolecularCA,
  title={Molecular cloning and physical mapping of the DNA of bovine adenovirus serotype 4; study of the DNA homology among bovine, human and porcine adenoviruses.},
  author={M Benk{\"o} and Bal{\'a}zs Harrach and J C D'halluin},
  journal={The Journal of general virology},
  year={1990},
  volume={71 ( Pt 2)},
  pages={465-9}
}
The DNA of bovine adenovirus (BAV) serotype 4, a member of the subgroup 2 BAVs, has been cloned and mapped with 11 restriction enzymes. Southern blot hybridizations probed by a clone containing about 50% of the BAV-4 genome revealed a very strong and extended DNA sequence homology amongst the members of subgroup 2, but no homology was detectable to the subgroup 1 bovine, or any of those human (HAV) and porcine adenovirus serotypes examined. These findings were strengthened by reciprocal… CONTINUE READING
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