Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family.

@article{Gillen1996MolecularCA,
  title={Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family.},
  author={Christopher M. Gillen and Suzanne Brill and John A. Payne and Biff Forbush},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 27},
  pages={
          16237-44
        }
}
  • Christopher M. Gillen, Suzanne Brill, +1 author Biff Forbush
  • Published in
    The Journal of biological…
    1996
  • Biology, Medicine
  • We report the cloning, sequence analysis, tissue distribution, and functional expression of the K-Cl cotransport protein, KCC1. KCC1 was identified by searching the human expressed sequence tag data base, based on the expectation that it would be distantly related to the Na-K-Cl cotransporter. Rabbit KCC1 (rbKCC1) and rat KCC1 (rtKCC1) were cloned by screening rabbit kidney and rat brain cDNA libraries using homologous cDNA probes. Human KCC1 (hKCC1) was obtained from I.M.A.G.E. clones and in… CONTINUE READING

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