Molecular cloning and functional characterization of Schistosoma japonicum enolase which is highly expressed at the schistosomulum stage

@article{Yang2010MolecularCA,
  title={Molecular cloning and functional characterization of Schistosoma japonicum enolase which is highly expressed at the schistosomulum stage},
  author={Jianmei Yang and Chunhui Qiu and Yanxun Xia and Lixiao Yao and Zhiqiang Fu and Chunxiu Yuan and Xingang Feng and Jiaojiao Lin},
  journal={Parasitology Research},
  year={2010},
  volume={107},
  pages={667-677}
}
Enolase is a key enzyme in the glycolytic pathway; recent studies have also shown that enolase is found on the surface of several parasites, where it acts as a plasminogen-binding protein. In the present study, the enolase of Schistosoma japonicum has been cloned and expressed. In western blot analysis, the recombinant enolase from S. japonicum ( rSjENO) was recognized by rabbit sera directed against an antigen preparation from adult worms. Kinetic measurement revealed that rSjENO possesses… CONTINUE READING