Molecular cloning and expression of the gene for a human D1 dopamine receptor

  title={Molecular cloning and expression of the gene for a human D1 dopamine receptor},
  author={A Dearry and Jay A Gingrich and Pierre Falardeau and Robert T. Fremeau and Michael D. Bates and Marc G. Caron},
THE diverse physiological actions of dopamine are mediated by its interaction with two basic types of G protein-coupled receptor, D1 and D2, which stimulate and inhibit, respectively, the enzyme adenylyl cyclase1. Alterations in the number or activity of these receptors may be a contributory factor in diseases such as Parkinson's disease and schizophrenia. Here we describe the isolation and characterization of the gene encoding a human D1 dopamine receptor. The coding region of this gene is… 

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

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Expression of the dopamine D2 receptor gene in brain

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Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor.

The cDNA for the Syrian hamster alpha 1-adrenergic receptor has been cloned with oligonucleotides corresponding to the partial amino acid sequence of the receptor protein purified from DDT1MF-2

Dopamine receptor subtypes: beyond the D1/D2 classification.

Dopamine receptors in the central nervous system.

Identification of two serine residues involved in agonist activation of the beta-adrenergic receptor.

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Expression of striatal D1 dopamine receptors coupled to inositol phosphate production and Ca2+ mobilization in Xenopus oocytes.

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