Molecular cloning and expression of the catalytic subunit of protein kinase A from Trypanosoma cruzi.

@article{Huang2002MolecularCA,
  title={Molecular cloning and expression of the catalytic subunit of protein kinase A from Trypanosoma cruzi.},
  author={Huan Huang and Craig Werner and Louis M Weiss and Murray Wittner and George Orr},
  journal={International journal for parasitology},
  year={2002},
  volume={32 9},
  pages={
          1107-15
        }
}
The activation of protein kinase A (cyclic adenosine monophosphate-dependent protein kinase) by cyclic adenosine monophosphate is believed to play an important role in regulating the growth and differentiation of Trypanosoma cruzi. A PCR using degenerate oligonucleotide primers against conserved motifs in the VIb and VIII subdomains of the ACG family of serine/threonine protein kinases was utilised to amplify regions corresponding to the parasite homologue of the protein kinase A catalytic… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-5 of 5 extracted citations

Cyclic-nucleotide signalling in protozoa.

FEMS microbiology reviews • 2011
View 5 Excerpts
Highly Influenced

Role of protein kinase A in Trypanosoma cruzi.

Infection and immunity • 2008
View 3 Excerpts
Highly Influenced

Inducible suicide vector systems for Trypanosoma cruzi.

Microbes and infection • 2015
View 2 Excerpts
Method Support