Molecular cloning and expression of murine thromboxane synthase.

@article{Zhang1993MolecularCA,
  title={Molecular cloning and expression of murine thromboxane synthase.},
  author={L Zhang and Michael B. Chase and R F Shen},
  journal={Biochemical and biophysical research communications},
  year={1993},
  volume={194 2},
  pages={
          741-8
        }
}
The complementary DNA (cDNA) for murine thromboxane synthase (TS) was isolated from a lung cDNA library. The full-length cDNA (1,910 bp) encodes a 533 amino acid protein (Mr 58,220) sharing 78% identity with human TS. Sequence comparison indicated that one of the two N-glycosylation sites, eight of the eleven cysteine residues, and a heme-binding domain are conserved in both murine and human TS sequences. The authenticity of the cDNA was confirmed by transient expression of a catalytically… Expand
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