Molecular cloning and expression of a unique receptor-like protein-tyrosine-phosphatase in the leucocyte-common-antigen-related phosphate family.

@article{Zhang1994MolecularCA,
  title={Molecular cloning and expression of a unique receptor-like protein-tyrosine-phosphatase in the leucocyte-common-antigen-related phosphate family.},
  author={Wen Ri Zhang and Naotake Hashimoto and Faiyaz Ahmad and Wei Ding and Barry J. Goldstein},
  journal={The Biochemical journal},
  year={1994},
  volume={302 ( Pt 1)},
  pages={39-47}
}
Protein-tyrosine-phosphatases (PTPases) have been implicated in the regulation of certain tyrosine kinase growth factor receptors in that they dephosphorylate the activated (autophosphorylated) form of the receptors. In order to identify PTPases that potentially act on receptor targets in liver, we used the human leucocyte common antigen-related PTPase (LAR) cDNA [Streuli, Krueger, Hall, Schlossman and Saito (1988) J. Exp. Med. 168, 1523-1530] and isolated two closely related transmembrane… CONTINUE READING