Molecular cloning and expression of Ehf, a new member of the ets transcription factor/oncoprotein gene family.

@article{Bochert1998MolecularCA,
  title={Molecular cloning and expression of Ehf, a new member of the ets transcription factor/oncoprotein gene family.},
  author={M A Bochert and L A Kleinbaum and Lan Y. Sun and Frank H. Burton},
  journal={Biochemical and biophysical research communications},
  year={1998},
  volume={246 1},
  pages={176-81}
}
The ets family is a large multigene family of transcription factors that share a conserved DNA-binding "ETS" domain and include several oncoproteins that induce tumorigenesis when overexpressed. Here we report the cDNA cloning from mouse pituitary somatotroph tumors, sequence characterization and tissue-specific expression pattern in mice of a novel ets family gene, "Ehf" ("ets homologous factor"). The putative 300 amino acid Ehf protein is a highly divergent ets family member, but is most… CONTINUE READING