Molecular cloning and expression in Pichia pastoris of a hypoallergenic antigen 5.

@article{Vinzn2010MolecularCA,
  title={Molecular cloning and expression in Pichia pastoris of a hypoallergenic antigen 5.},
  author={Sabrina E Vinz{\'o}n and Mar{\'i}a L Pirpignani and Cristina Nowicki and Mirtha J Biscoglio de Jim{\'e}nez Bonino},
  journal={Protein expression and purification},
  year={2010},
  volume={73 1},
  pages={23-30}
}
Stings by insects from the Hymenoptera order can cause life-threatening allergic reactions and impair life quality. Immunotherapy with venom extracts is the most extensively employed treatment to reduce morbidity and mortality, but purified and safer allergy vaccines are needed. Antigen 5 is an important allergen of vespid venoms. We previously reported that Antigen 5 from Polybia scutellaris (Poly s 5) is likely to be a hypoallergenic variant. On the basis of such findings, this work deals… CONTINUE READING