Molecular cloning and chromosomal assignment of the mouse C-type natriuretic peptide (CNP) gene (Nppc): comparison with the human CNP gene (NPPC).

@article{Ogawa1994MolecularCA,
  title={Molecular cloning and chromosomal assignment of the mouse C-type natriuretic peptide (CNP) gene (Nppc): comparison with the human CNP gene (NPPC).},
  author={Yoshio Ogawa and Hirotaka Itoh and Yoshimasa Yoshitake and Masayuki Inoue and Takaaki Yoshimasa and Tadao Serikawa and Kenji Nakao},
  journal={Genomics},
  year={1994},
  volume={24 2},
  pages={383-7}
}
The mouse C-type natriuretic peptide (CNP) genomic fragment was isolated from a mouse genomic DNA library. The mouse CNP gene is composed of at least two exons and one intron. The 5'-flanking region contains an array of cis-acting regulatory elements and a dinucleotide CA repeat (microsatellite). Analysis of the deduced amino acid sequences revealed that mouse preproCNP is a 126-amino-acid peptide and that its C-terminal 22-residue peptide preceded by Lys-Lys is identical to porcine, rat, and… CONTINUE READING

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