Molecular cloning and characterization of the neonatal rat and mouse submandibular gland protein SMGC.

@article{Zinzen2004MolecularCA,
  title={Molecular cloning and characterization of the neonatal rat and mouse submandibular gland protein SMGC.},
  author={Karen M Zinzen and Arthur R Hand and Maya Yankova and William D Ball and Lily Mirels},
  journal={Gene},
  year={2004},
  volume={334},
  pages={23-33}
}
We report the molecular cloning and characterization of SMGC, a major secretory product and a marker of the type I (terminal tubule) cells of the neonatal rat and mouse submandibular gland. SMGC is expressed in the submandibular gland at high levels through postnatal day 20, but in the adult is present only in some intercalated duct cells. Rat and mouse SMGC have deduced molecular weights of 67.8 and 74.4 kDa, respectively, are 37% Ser+Gly+Thr, and contain tandem repeats of between 8 and 60… CONTINUE READING