Molecular cloning and characterization of the gene encoding human NeuroD

@article{Yoon1998MolecularCA,
  title={Molecular cloning and characterization of the gene encoding human NeuroD},
  author={Yong-Shik Yoon and T. Noma and Y. Yamashiro and H. Ito and A. Nakazawa},
  journal={Neuroscience Letters},
  year={1998},
  volume={251},
  pages={17-20}
}
  • Yong-Shik Yoon, T. Noma, +2 authors A. Nakazawa
  • Published 1998
  • Biology, Medicine
  • Neuroscience Letters
    • NeuroD is a basic helix-loop-helix transcription factor that binds to an E-box sequence, CANNTG, in the target gene promoter region. The gene encoding NeuroD is expressed specifically in brain, intestine, and pancreatic cells and plays a pivotal role in tissue-specific differentiation. To investigate the regulation of human NeuroD gene expression, we isolated and sequenced a genomic DNA containing two exons and flanking regions of the NeuroD gene. The sizes of exons 1 and 2 were 168 and 2404 bp… CONTINUE READING
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    16 Citations
    Background Citations
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    Methods Citations
    1
    16 Citations
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    References

    SHOWING 1-10 OF 12 REFERENCES
    NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family.
    • 171
    • PDF
    Molecular cloning of a human neuroD from a neuroblastoma cell line specifically expressed in the fetal brain and adult cerebellum.
    • 27
    Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein.
    • 1,032
    Basic helix-loop-helix genes in neural development
    • J. Lee
    • Biology, Medicine
    • Current Opinion in Neurobiology
    • 1997
    • 524
    • PDF
    Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers.
    • 220
    • PDF
    HLH proteins, fly neurogenesis, and vertebrate myogenesis
    • 410
    Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences
    • 78
    Transcription factor AP-2 essential for cranial closure and craniofacial development
    • 586
    Full-length cDNA cloning and determination of mRNA 5' and 3' ends by amplification of adaptor-ligated cDNA.
    • 170
    High efficiency gene transfer into mammalian cells.
    • C. Gorman, D. Lane, P. Rigby
    • Biology, Medicine
    • Philosophical transactions of the Royal Society of London. Series B, Biological sciences
    • 1984
    • 501