Molecular cloning and characterization of the SIFamide precursor and receptor in a hymenopteran insect, Bombus terrestris.

@article{Lismont2018MolecularCA,
  title={Molecular cloning and characterization of the SIFamide precursor and receptor in a hymenopteran insect, Bombus terrestris.},
  author={Els Lismont and Nele Mortelmans and Heleen Verlinden and Jozef Vanden Broeck},
  journal={General and comparative endocrinology},
  year={2018},
  volume={258},
  pages={
          39-52
        }
}
SIFamides (SIFa) are a family of neuropeptides that are highly conserved among arthropods. In insects, this peptide is mainly expressed in four medial interneurons in the pars intercerebralis and affects sexual behavior, sleep regulation and pupal mortality. Furthermore, an influence on the hatching rate has been observed. The first SIFa receptor (SIFR) was pharmacologically characterized in Drosophila melanogaster and is homologous to the vertebrate gonadotropin-inhibitory hormone (GnIH… CONTINUE READING