Molecular cloning and characterization of the RNA packaging-defective retrovirus SE21Q1b.

@article{Anderson1992MolecularCA,
  title={Molecular cloning and characterization of the RNA packaging-defective retrovirus SE21Q1b.},
  author={Donovan J Anderson and Peter P. Lee and K L Levine and Junbaio Sang and Sayed A Shah and Otto O Yang and Peter R. Shank and Maxine L. Linial},
  journal={Journal of virology},
  year={1992},
  volume={66 1},
  pages={204-16}
}
The nonconditional RNA packaging mutant SE21Q1b contains cis- and trans-acting defects which cause cellular mRNA, rather than viral genomic RNA, to be nonspecifically packaged into SE21Q1b viral particles. Using genomic libraries of the c-SE21Q1b quail cell line, we have been able to construct a molecular clone of the SE21Q1b provirus. Upon transfection… CONTINUE READING