Molecular cloning and characterization of rat V1b vasopressin receptor: evidence for its expression in extra-pituitary tissues.

@article{Saito1995MolecularCA,
  title={Molecular cloning and characterization of rat V1b vasopressin receptor: evidence for its expression in extra-pituitary tissues.},
  author={Mutsuo Saito and Toshitsugu Sugimoto and Atsuo Tahara and Hiroyuki Kawashima},
  journal={Biochemical and biophysical research communications},
  year={1995},
  volume={212 3},
  pages={751-7}
}
Arginine vasopressin (AVP) modulates the secretion of ACTH through vasopressin receptor subtype V1b in the pituitary. We recently cloned human V1b, but several inconsistencies were found between the characteristics of this cloned receptor and those of rat pituitary membrane shown by previous workers. To clarify this issue, we report here the molecular cloning and functional expression of the cDNA encoding V1b in rat pituitary. This receptor encodes 425 amino acid protein having the highest… CONTINUE READING
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