Molecular cloning and characterization of murine interleukin-11.


Human interleukin-11 (IL-11) has been shown to have pleiotropic action on hematopoietic, hepatic, stromal, epithelial, neural, and osteoclast cells. In the present work, the murine IL-11 cDNA has been isolated from a fetal thymic cell line, and its structure and function compared with human IL-11. The murine protein was demonstrated to have identical… (More)


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@article{Morris1996MolecularCA, title={Molecular cloning and characterization of murine interleukin-11.}, author={J. C. Morris and Steven S Neben and F. E. Bennett and Heather Finnerty and A. Long and D Beier and S. Kovacic and J. Michael McCoy and Elizabeth A. DiBlasio-Smith and E R La Vallie and Arnaldo Caruso and James Calvetti and Gareth A Morris and Nadine Weich and Subrato Paul and Philip S. Crosier and K. J. Turner and C. R. Wood}, journal={Experimental hematology}, year={1996}, volume={24 12}, pages={1369-76} }