Molecular cloning and characterization of a porcine UL16 binding protein (ULBP)-like cDNA.

@article{GarcaBorges2005MolecularCA,
  title={Molecular cloning and characterization of a porcine UL16 binding protein (ULBP)-like cDNA.},
  author={Carmen N. Garc{\'i}a-Borges and Bounleut Phanavanh and Sarika Saraswati and Richard A Dennis and Mark D. Crew},
  journal={Molecular immunology},
  year={2005},
  volume={42 6},
  pages={
          665-71
        }
}
UL16 binding proteins (ULBPs) are ligands for the NK cell activating receptor NKG2D. A cDNA encoding a porcine ULBP-like protein (PULBP) was cloned and the predicted amino acid sequence exhibited 35-52% identity to human ULBPs. Southern blot analysis suggested that there is only one ULBP-like gene in the pig genome. Transcripts of PULBP and another potential NKG2D ligand, MIC2, were detected by RT-PCR in a wide range of tissues. Recombinant PULBP-Fc and human ULBP2-Fc fusion proteins were made… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 27 REFERENCES

Sequence of the swine major histocompatibility complex region containing all non-classical class I genes

P. Chardon, C. Rogel-Gaillard, +3 authors C. Renard
  • Tissue Antigens
  • 2001
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Effects of human cytomegalovirus infection on ligands for the activating NKG2D receptor of NK cells: up-regulation of UL16-binding protein (ULBP)1 and ULBP2 is counteracted by the viral UL16 protein

A. Rolle, M. Mousavi-Jazi, +5 authors C. Cerboni
  • J. Immunol
  • 2003
VIEW 1 EXCERPT

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