Molecular cloning and characterization of a novel casein kinase II substrate, HASPP28, from rat brain.

@article{Shen1996MolecularCA,
  title={Molecular cloning and characterization of a novel casein kinase II substrate, HASPP28, from rat brain.},
  author={L. Shen and K. Huang and H. Chen and F. Huang},
  journal={Archives of biochemistry and biophysics},
  year={1996},
  volume={327 1},
  pages={
          131-41
        }
}
HASPP28 (heat- and acid-stable phosphoprotein of 28 kDa) has been purified to near homogeneity from the acid-stable protein fraction of rat brain extract. Based on the N-terminal 40 amino acid sequence, a pair of highly degenerate primers was used to generate a 107-bp probe from rat brain RNA by RT-PCR. From the rat brain lambda gt11 library, this probe identified two positive clones that together provided a cDNA of 837 bp with an open reading frame of 546 bp. This cDNA was extended by 3'RACE… Expand
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