Molecular cloning and characterization of a metal responsive Aedes aegypti intestinal mucin cDNA.

@article{RaymsKeller2000MolecularCA,
  title={Molecular cloning and characterization of a metal responsive Aedes aegypti intestinal mucin cDNA.},
  author={Alfredo Rayms-Keller and M M McGaw and C. T. Oray and Jon O. Carlson and Barry J Beaty},
  journal={Insect molecular biology},
  year={2000},
  volume={9 4},
  pages={419-26}
}
We have isolated a cDNA from Aedes aegypti that is transcribed in the larval midgut in response to metal exposure, and in the adult female midgut in response to iron or cadmium exposure, or a blood meal. The cDNA encodes a protein, designated Aedes aegypti intestinal mucin 1 (AEIMUC1), which has similarities with invertebrate intestinal mucins and peritrophins, and vertebrate mucins. Proline, serine and threonine comprise 30% of the amino acid composition of AEIMUC1, a characteristic of mucins… CONTINUE READING

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