Molecular cloning and characterization of CT120, a novel membrane-associated gene involved in amino acid transport and glutathione metabolism.

@article{He2002MolecularCA,
  title={Molecular cloning and characterization of CT120, a novel membrane-associated gene involved in amino acid transport and glutathione metabolism.},
  author={Xianghuo He and Yujun Di and Jinjun Li and Yihu Xie and Yuntian Tang and Fengrui Zhang and Lin Heng Wei and Yu Zhang and Wenxin Qin and Keke Huo and Yuyang Li and Dafang Wan and Jianren Gu},
  journal={Biochemical and biophysical research communications},
  year={2002},
  volume={297 3},
  pages={528-36}
}
Within the minimum LOH region on chromosome 17p13.3 deleted in hepatocellular carcinoma, a novel human plasma membrane-associated gene, named CT120, was isolated from a human kidney cDNA library using electronical cloning and RACE. The novel gene CT120 consists of 2145bp and encodes a protein with 257 amino acids. Database search revealed that homologs of CT120 exist in different organisms from plant to animal kingdoms, which suggests that CT120 is a highly conserved gene during biological… CONTINUE READING