Molecular cloning and analysis of the 5'-flanking region of the rat PP1 alpha gene.

@article{Nomoto1996MolecularCA,
  title={Molecular cloning and analysis of the 5'-flanking region of the rat PP1 alpha gene.},
  author={Ken ‘ ichi Nomoto and Nobuto Shibata and Kenji Kitamura and Yusuke Mizuno and Kaoru Kikuchi},
  journal={Biochimica et biophysica acta},
  year={1996},
  volume={1309 3},
  pages={221-5}
}
We have cloned an 8 kbp genomic fragment of 5'-flanking region of the gene encoding the catalytic subunit of rat protein phosphatase 1 alpha. Neither CAAT box nor TATA box was detected but a 300 bp high GC region containing nine Sp1 transcription factor binding sites is present immediately upstream of the translation start site, demonstrating that PP1 alpha is a housekeeping gene. Luciferase reporter assay showed that transcription of PP1 alpha is controlled at the high GC region. 

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