Molecular cloning, sequencing, tissue distribution, and functional expression of a Na+/H+ exchanger (NHE-2).

@article{Collins1993MolecularCS,
  title={Molecular cloning, sequencing, tissue distribution, and functional expression of a Na+/H+ exchanger (NHE-2).},
  author={James F Collins and Toshiyuki Honda and Susan M. Knobel and Nada Bulus and Jon T Conary and Raymond Dubois and Fayez K. Ghishan},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 9},
  pages={3938-42}
}
The present studies demonstrate cloning, sequencing, tissue distribution, and functional expression of a Na+/H+ exchanger which was isolated from a rat intestinal cDNA library. The cloned cDNA recognizes two transcripts in poly(A)+ RNA from the stomach, jejunum, ileum, liver, large intestine, and uterus. Based on deduced amino acid sequences, this clone shares sequence homology with the other known Na+/H+ exchanger isoforms (NHE-1, NHE-3, and NHE-4) except for its 5' end. Overall, the protein… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 46 extracted citations

The Sodium-Hydrogen Exchanger

View 8 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…