Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor.

@article{Wellendorph2004MolecularCE,
  title={Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor.},
  author={Petrine Wellendorph and Hans Br{\"a}uner-Osborne},
  journal={Gene},
  year={2004},
  volume={335},
  pages={37-46}
}
By similarity searching of the human genome sequence using known family C G-protein-coupled receptors (GPCRs) as query sequences, we have identified a putative novel human gene product of unknown function (located on chromosome band 6q22.31). The transcript, entitled GPRC6A (isoform 1), was cloned from a human kidney cDNA (DNA complementary to RNA) library and shown to encode a protein of 926 amino acids (aa). Protein sequence analysis revealed the presence of a seven-transmembrane (7TM) domain… CONTINUE READING

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