Molecular cloning, characterization, and expression analysis of p53 from the oriental river prawn, Macrobrachium nipponense, in response to hypoxia.

Abstract

The tumor suppressor gene p53 plays a critical role in safeguarding the integrity of the genome in mammalian cells. It acts as a sequence-specific transcription factor. Once p53 is activated by a variety of cellular stresses, it transactivates downstream target genes and regulates the cell cycle and apoptosis. However, little is known about the functions of… (More)
DOI: 10.1016/j.fsi.2016.03.167

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@article{Sun2016MolecularCC, title={Molecular cloning, characterization, and expression analysis of p53 from the oriental river prawn, Macrobrachium nipponense, in response to hypoxia.}, author={Shengming Sun and Zhimin Gu and Hongtuo Fu and Jian Zhu and Xianping Ge and Fujun Xuan}, journal={Fish & shellfish immunology}, year={2016}, volume={54}, pages={68-76} }