Molecular classification of gliomas based on whole genome gene expression: a systematic report of 225 samples from the Chinese Glioma Cooperative Group.

@article{Yan2012MolecularCO,
  title={Molecular classification of gliomas based on whole genome gene expression: a systematic report of 225 samples from the Chinese Glioma Cooperative Group.},
  author={Wei Yan and Wei Jun Zhang and Gan You and Junxia Zhang and Lei Han and Zhaoshi Bao and Yongzhi Wang and Yanwei Liu and Chuanlu Jiang and Chunsheng Kang and Yongping You and Tao Jiang},
  journal={Neuro-oncology},
  year={2012},
  volume={14 12},
  pages={1432-40}
}
Defining glioma subtypes based on objective genetic and molecular signatures may allow for a more rational, patient-specific approach to molecularly targeted therapy. However, prior studies attempting to classify glioma subtypes have given conflicting results. We aim to complement and validate the existing molecular classification system on a large number of samples from an East Asian population. A total of 225 samples from Chinese patients was selected for whole genome gene expression… CONTINUE READING