Molecular characterization of three new virulent Newcastle disease virus variants isolated in China.

Abstract

Three cases of Newcastle disease virus (NDV) found in nature had the lentogenic motif (112)G-R-Q-G-R-L(117) in their fusion protein cleavage sites. However, both intracerebral pathogenicity and intravenous pathogenicity indexes showed that these NDV isolates were virulent. In comparison with the LaSota live virus vaccine, these viruses had significant genetic variations in the hemagglutinin-neuraminidase gene.

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Cite this paper

@article{Tan2008MolecularCO, title={Molecular characterization of three new virulent Newcastle disease virus variants isolated in China.}, author={Lei-Tao Tan and Huai-ying Xu and You-ling Wang and Zhuo-ming Qin and Lei Sun and Wenjun Liu and Zhi-zhong Cui}, journal={Journal of clinical microbiology}, year={2008}, volume={46 2}, pages={750-3} }